What's the best way to hang a BIG painting on the wall?

We've just moved and have alot of wall space. We want to put a painting up without people seeing the nails and stuff. how do you do it?What's the best way to hang a BIG painting on the wall?
You will need to use wall anchors so they don't come out from the weight of the picture, and use the wire on the back of the painting because it will be easier to adjust it in case you get it a little crooked.What's the best way to hang a BIG painting on the wall?
Try the 3M wall hangers. There's one made for what you need.
Hire an artist to paint the picture directly on the wall.
with BIG nails and wire